No. 6 Washington (-5.5) vs. No. 23 Washington State

When: Friday, 3:30 p.m. ET (Fox Sports 1)

The Huskies are a better team at home, but defense travels. I think the Huskies will win this game on the ground.

Pick: Washington (-5.5)


No. 17 Nebraska vs. Iowa (-3)

When: Friday, 3:30 p.m. ET (ABC)

Nebraska has been struggling without QB Tommy Armstrong, but even if he does play he will be rusty. I like Iowa in this one.

Pick: Iowa (-3)


No. 20 Boise State (-9.5) vs. Air Force

WhenFriday, 3:30 p.m. ET (CBS Sports Network)

Boise state’s New Years Bowl aspirations have taken a significant hit over the last three weeks. Air Force is a good team, and I think 9.5 points is too much to give them.

Pick: Air Force (+9.5)


Toledo vs. No. 14 Western Michigan (-9)

WhenFriday, 5 p.m. ET (ESPNU)

These are the two best teams in the MAC by far. Western Michigan giving 9 points is a lot here, but I think they will cover.

Pick: Western Michigan (-9)


No. 3 Michigan vs. No. 2 Ohio State (-6.5)

When: Saturday, noon ET (ABC)

Michigan has a great defense, but in the end, I think Ohio State will be able to run the ball on the edges and win the game comfortably.

Pick: Ohio State (-6)


Kentucky vs. No. 11 Louisville (-23)

When: Saturday, noon ET (ESPN)

23 points is a lot of points, but I look for the Cardinals to come out flying and overwhelm the Cats.

Pick: Louisville (-23)


No. 16 Auburn vs. No. 1 Alabama (-18)

WhenSaturday, 3:30 p.m. ET (CBS)

This game will have to be won by the arm of Jalen Hurts, which means 18 points is way too much to give. The Tide win but not by 18.

Pick: Auburn (+18)


Minnesota vs. No. 5 Wisconsin (-14)

WhenSaturday, 3:30 p.m. ET (Big Ten Network)

Wisconsin takes this easy; I don’t see how Minnesota can score points against Wisconsin’s defense.

Pick: Wisconsin (-14)


Michigan State vs. No. 8 Penn State (-12)

WhenSaturday, 3:30 p.m. ET (ESPN)

Penn State is undefeated at home, and I think they win, just not by 12 points.

Pick: Michigan State (+12)


Notre Dame vs. No. 12 USC (-17)

WhenSaturday, 3:30 p.m. ET (ABC)

This should be Brian Kelly’s last game, and it won’t be a pretty one.

Pick: USC (-17)


No. 13 Florida vs. No. 15 Florida State (-7)

When: Saturday, 8 p.m. ET (ABC)

Florida is great on defense, but they do not have enough offense to hang with the Seminoles.

Pick: Florida State (-7)